AFfirm™ TBX22 Mouse Monoclonal Antibody - #BF9315
製品説明
ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human
クローナリティ:
Monoclonal [AFfirm9315]
特異性:
TBX22 Mouse Monoclonal Antibody detects endogenous levels of total TBX22.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
ABERS; CLPA; CPX; D230020M15Rik; dJ795G23.1; T box 22; T box protein 22; T box transcription factor TBX22; T-box protein 22; T-box transcription factor TBX22; Tbx22; TBX22_HUMAN; TBXX;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質の説明:
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis.
タンパク質配列:
- Q9Y458 TBX22_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
PTMs - Q9Y458 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K63 | Sumoylation | Uniprot | |
| T68 | Phosphorylation | Uniprot | |
| S69 | Phosphorylation | Uniprot | |
| S72 | Phosphorylation | Uniprot | |
| S78 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| S84 | Phosphorylation | Uniprot | |
| S86 | Phosphorylation | Uniprot | |
| Y138 | Phosphorylation | Uniprot | |
| T243 | Phosphorylation | Uniprot | |
| T268 | Phosphorylation | Uniprot | |
| K271 | Sumoylation | Uniprot |
研究背景
機能:
Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.
細胞の位置付け:
Nucleus.
組織特異性:
Seems to be expressed at a low level.
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For Research Use Only.
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