製品: NUFIP1 Mouse Monoclonal Antibody
カタログ: BF8832
タンパク質の説明: Mouse monoclonal antibody to NUFIP1
アプリケーション: WB
反応性: Human
予測: Mouse, Rat, Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
分子量: 70-75 kDa; 56kD(Calculated).
ユニプロット: Q9UHK0

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8832]
特異性:
NUFIP1 Mouse Monoclonal Antibody detects endogenous levels of total NUFIP1.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

bA540M5.1; Nuclear FMRP interacting protein 1; Nuclear fragile X mental retardation interacting protein 1; nuclear fragile X mental retardation protein interacting protein 1; NUFIP;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9UHK0 NUFP1_HUMAN:

Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.

タンパク質配列:
MAEPTSDFETPIGWHASPELTPTLGPLSDTAPPRDSWMFWAMLPPPPPPLTSSLPAAGSKPSSESQPPMEAQSLPGAPPPFDAQILPGAQPPFDAQSPLDSQPQPSGQPWNFHASTSWYWRQSSDRFPRHQKSFNPAVKNSYYPRKYDAKFTDFSLPPSRKQKKKKRKEPVFHFFCDTCDRGFKNQEKYDKHMSEHTKCPELDCSFTAHEKIVQFHWRNMHAPGMKKIKLDTPEEIARWREERRKNYPTLANIERKKKLKLEKEKRGAVLTTTQYGKMKGMSRHSQMAKIRSPGKNHKWKNDNSRQRAVTGSGSHLCDLKLEGPPEANADPLGVLINSDSESDKEEKPQHSVIPKEVTPALCSLMSSYGSLSGSESEPEETPIKTEADVLAENQVLDSSAPKSPSQDVKATVRNFSEAKSENRKKSFEKTNPKRKKDYHNYQTLFEPRTHHPYLLEMLLAPDIRHERNVILQCVRYIIKKDFFGLDTNSAKSKDV

PTMs - Q9UHK0 基板として

Site PTM Type Enzyme
R126 Methylation
S133 Phosphorylation
S205 Phosphorylation
K229 Sumoylation
T232 Phosphorylation
Y247 Phosphorylation
K257 Acetylation
K260 Acetylation
K265 Acetylation
T271 Phosphorylation
S292 Phosphorylation
S312 Phosphorylation
S338 Phosphorylation
S340 Phosphorylation
S342 Phosphorylation
S351 Phosphorylation
S366 Phosphorylation
S367 Phosphorylation
Y368 Phosphorylation
S403 Phosphorylation
S405 Phosphorylation
Y476 Phosphorylation
T487 Phosphorylation
S489 Phosphorylation

研究背景

機能:

Binds RNA.

細胞の位置付け:

Nucleus.
Note: Distributed in the nucleus in a dot-like pattern.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.

サブユニット構造:

Interacts with FMR1. Interacts with ZNHIT3.

Restrictive clause

 

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