| 製品: | FRA2 Mouse Monoclonal Antibody |
| カタログ: | BF8276 |
| タンパク質の説明: | Mouse monoclonal antibody to FRA2 |
| アプリケーション: | ELISA(peptide) |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 35-45kD(Observed); 35kD(Calculated). |
| ユニプロット: | P15408 |
Control Products
製品説明
ソース:
Mouse IgG
反応性:
Human, Mouse, Rat
クローナリティ:
Monoclonal [AFfirm8276]
特異性:
FRA2 Mouse Monoclonal Antibody detects endogenous levels of total FRA2
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
FLJ23306; Fos L2; FOS like antigen 2; Fos related antigen 2; Fos-related antigen 2; FosL 2; Fosl2; FOSL2_HUMAN; FRA 2; FRA-2;
免疫原
免疫原:
A synthesized peptide derived from human FRA2, corresponding to a region within C-terminal amino acids.
Uniprot:
遺伝子(ID):
タンパク質の説明:
Controls osteoclast survival and size (By similarity). As a dimer with JUN, activates LIF transcription (By similarity). Activates CEBPB transcription in PGE2-activated osteoblasts.
タンパク質配列:
- P15408 FOSL2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL
研究背景
機能:
Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts.
細胞の位置付け:
Nucleus.
タンパク質ファミリー:
Belongs to the bZIP family. Fos subfamily.
研究領域
· Organismal Systems > Development > Osteoclast differentiation. (View pathway)
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