製品: SFRS18 Mouse Monoclonal Antibody
カタログ: BF8118
タンパク質の説明: Mouse monoclonal antibody to SFRS18
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 93kDa; 93kD(Calculated).
ユニプロット: Q8TF01

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Monoclonal [AFfirm8118]
特異性:
SFRS18 Antibody detects endogenous levels of total SFRS18.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q8TF01 PNISR_HUMAN:

Expressed in heart, skeletal muscle, thymus, spleen, kidney, liver, placenta and leukocytes.

タンパク質配列:
MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGMMPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR

PTMs - Q8TF01 基板として

Site PTM Type Enzyme
S204 Phosphorylation
S211 Phosphorylation
K218 Sumoylation
K228 Ubiquitination
K266 Acetylation
T271 Phosphorylation
S286 Phosphorylation
S290 Phosphorylation
S304 Phosphorylation
S305 Phosphorylation
T309 Phosphorylation
S311 Phosphorylation
S313 Phosphorylation
S321 Phosphorylation
T326 Phosphorylation
S393 Phosphorylation
S396 Phosphorylation
S401 Phosphorylation
S405 Phosphorylation
S407 Phosphorylation
S408 Phosphorylation
T410 Phosphorylation
S465 Phosphorylation
S467 Phosphorylation
T485 Phosphorylation
T489 Phosphorylation
S517 Phosphorylation
S518 Phosphorylation
S522 Phosphorylation
T524 Phosphorylation
T527 Phosphorylation
S529 Phosphorylation
T530 Phosphorylation
S532 Phosphorylation
S533 Phosphorylation
S537 Phosphorylation
S539 Phosphorylation
S540 Phosphorylation
S561 Phosphorylation
S563 Phosphorylation
S571 Phosphorylation
S573 Phosphorylation
S575 Phosphorylation
S577 Phosphorylation
S597 Phosphorylation
S601 Phosphorylation
S611 Phosphorylation
S613 Phosphorylation
S621 Phosphorylation
S623 Phosphorylation
S634 Phosphorylation
S636 Phosphorylation
S650 Phosphorylation
S672 Phosphorylation
S705 Phosphorylation
S706 Phosphorylation
S722 Phosphorylation
S724 Phosphorylation
S726 Phosphorylation
K730 Acetylation
S752 Phosphorylation

研究背景

細胞の位置付け:

Nucleus speckle.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in heart, skeletal muscle, thymus, spleen, kidney, liver, placenta and leukocytes.

サブユニット構造:

Interacts with PNN.

タンパク質ファミリー:

Belongs to the splicing factor SR family.

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