AFfirm™ RHOF Mouse Monoclonal Antibody - #BF8105
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
ARHF; FLJ20247; Ras homolog gene family member F (in filopodia); Ras homolog gene family member F; Rho F; Rho family GTPase Rif; Rho in filopodia; Rho related GTP binding protein RhoF; Rho-related GTP-binding protein RhoF; Rhof; RHOF_HUMAN; RIF;
免疫原
- Q9HBH0 RHOF_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKAQRQKKRRLCLLL
PTMs - Q9HBH0 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| T10 | Phosphorylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| S51 | Phosphorylation | Uniprot | |
| T61 | Phosphorylation | Uniprot | |
| S64 | Phosphorylation | Uniprot | |
| Y72 | Phosphorylation | Uniprot | |
| T74 | Phosphorylation | Uniprot | |
| Y80 | Phosphorylation | Uniprot | |
| K132 | Ubiquitination | Uniprot | |
| K190 | Ubiquitination | Uniprot | |
| K197 | Ubiquitination | Uniprot |
研究背景
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology.
Cell membrane>Lipid-anchor>Cytoplasmic side. Cytoplasm>Cytoskeleton.
Belongs to the small GTPase superfamily. Rho family.
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