AFfirm™ ABHD3 Mouse Monoclonal Antibody - #BF8097
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
ABHD3; Abhydrolase domain containing 3; Abhydrolase domain containing protein 3; Alpha/beta hydrolase domain containing protein 3; LABH3; Lung alpha/beta hydrolase 3; MGC11259;
免疫原
- Q8WU67 ABHD3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MQRLAMDLRMLSRELSLYLEHQVRVGFFGSGVGLSLILGFSVAYAFYYLSSIAKKPQLVTGGESFSRFLQDHCPVVTETYYPTVWCWEGRGQTLLRPFITSKPPVQYRNELIKTADGGQISLDWFDNDNSTCYMDASTRPTILLLPGLTGTSKESYILHMIHLSEELGYRCVVFNNRGVAGENLLTPRTYCCANTEDLETVIHHVHSLYPSAPFLAAGVSMGGMLLLNYLGKIGSKTPLMAAATFSVGWNTFACSESLEKPLNWLLFNYYLTTCLQSSVNKHRHMFVKQVDMDHVMKAKSIREFDKRFTSVMFGYQTIDDYYTDASPSPRLKSVGIPVLCLNSVDDVFSPSHAIPIETAKQNPNVALVLTSYGGHIGFLEGIWPRQSTYMDRVFKQFVQAMVEHGHELS
PTMs - Q8WU67 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K55 | Ubiquitination | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| Y156 | Phosphorylation | Uniprot | |
| Y169 | Phosphorylation | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| K297 | Ubiquitination | Uniprot | |
| K299 | Ubiquitination | Uniprot | |
| K332 | Ubiquitination | Uniprot | |
| K395 | Ubiquitination | Uniprot |
研究背景
Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids.
Membrane>Single-pass type II membrane protein.
Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
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