AFfirm™ Prohibitin Mouse Monoclonal Antibody - #BF8085
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB_HUMAN; PHB1; Prohibitin;
免疫原
A synthesized peptide derived from human Prohibitin, corresponding to a region within the internal amino acids.
- P35232 PHB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
PTMs - P35232 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K4 | Acetylation | Uniprot | |
| K4 | Methylation | Uniprot | |
| K4 | Ubiquitination | Uniprot | |
| K11 | Methylation | Uniprot | |
| R41 | Methylation | Uniprot | |
| S82 | Phosphorylation | Uniprot | |
| K83 | Ubiquitination | Uniprot | |
| T91 | Phosphorylation | Uniprot | |
| R93 | Methylation | Uniprot | |
| S101 | Phosphorylation | Uniprot | |
| T108 | Phosphorylation | Uniprot | |
| S109 | Phosphorylation | Uniprot | |
| Y114 | Phosphorylation | P06213 (INSR) | Uniprot |
| S121 | O-Glycosylation | Uniprot | |
| T123 | Phosphorylation | Uniprot | |
| K128 | Acetylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| K177 | Ubiquitination | Uniprot | |
| K186 | Ubiquitination | Uniprot | |
| K202 | Acetylation | Uniprot | |
| K202 | Ubiquitination | Uniprot | |
| K207 | Acetylation | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| S213 | Phosphorylation | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| K219 | Ubiquitination | Uniprot | |
| K240 | Ubiquitination | Uniprot | |
| Y249 | Phosphorylation | Uniprot | |
| S252 | Phosphorylation | Uniprot | |
| S254 | Phosphorylation | Uniprot | |
| T258 | O-Glycosylation | Uniprot | |
| T258 | Phosphorylation | P31749 (AKT1) | Uniprot |
| Y259 | Phosphorylation | Uniprot | |
| S265 | Phosphorylation | Uniprot |
研究背景
Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
Mitochondrion inner membrane. Nucleus.
Widely expressed in different tissues.
Interacts with PHB2. Interacts with STOML2.
Belongs to the prohibitin family.
Restrictive clause
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For Research Use Only.
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