| 製品: | CCNK Mouse Monoclonal Antibody |
| カタログ: | BF8073 |
| タンパク質の説明: | Mouse monoclonal antibody to CCNK |
| アプリケーション: | ELISA(peptide) |
| 反応性: | Human, Mouse |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 64 kDa(Observed); 64kD(Calculated). |
| ユニプロット: | O75909 |
Control Products
製品説明
ソース:
Mouse IgG
反応性:
Human, Mouse
クローナリティ:
Monoclonal [AFfirm8073]
特異性:
CCNK Antibody detects endogenous levels of total CCNK.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
CCNK; CCNK_HUMAN; CPR 4; CPR4; Cyclin K; Cyclin-K; CyclinK; MGC9113;
免疫原
免疫原:
A synthesized peptide derived from human CCNK, corresponding to a region within N-terminal amino acids.
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質の説明:
May play a role in transcriptional regulation. In vitro, is associated with a kinase activity toward both RNA polymerase II C-terminal domain and CDK2 (CAK)
タンパク質配列:
- O75909 CCNK_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR
研究背景
機能:
Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A).
細胞の位置付け:
Nucleus.
組織特異性:
Widely expressed. Highest levels in testis.
タンパク質ファミリー:
Belongs to the cyclin family. Cyclin C subfamily.
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