製品: AKR1CL2 Mouse Monoclonal Antibody
カタログ: BF8061
タンパク質の説明: Mouse monoclonal antibody to AKR1CL2
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit
分子量: 37 KD; 37kD(Calculated).
ユニプロット: Q96JD6

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:1000-1:10000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Monoclonal [AFfirm8061]
特異性:
AKR1CL2 Antibody detects endogenous levels of total AKR1CL2.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

1; 1,5-anhydro-D-fructose reductase; 5-anhydro-D-fructose reductase; AF reductase; AKCL2_HUMAN; AKR1CL2; Akr1e2; AKRDC1; Aldo keto reductase family 1 member C like protein 2; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; HTSP; LoopADR; Testis specific protein; Testis-specific protein;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q96JD6 AKCL2_HUMAN:

Specifically expressed in testis (PubMed:12604216, PubMed:15118078). Expressed in testicular germ cells and testis interstitial cells (PubMed:15118078).

タンパク質配列:
MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHKDYPFHIEY

PTMs - Q96JD6 基板として

Site PTM Type Enzyme
K183 Ubiquitination
T218 Phosphorylation

研究背景

機能:

Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro).

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Specifically expressed in testis. Expressed in testicular germ cells and testis interstitial cells.

サブユニット構造:

Monomer.

タンパク質ファミリー:

Belongs to the aldo/keto reductase family.

Restrictive clause

 

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