AFfirm™ TRIM59 Mouse Monoclonal Antibody - #BF8055
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
2310035M22Rik; 2700022F13Rik; MGC129860; MGC129861; MGC26631; MRF1; RING finger protein 104; RNF104; TRI59_HUMAN; TRIM57; TRIM59; Tripartite motif containing 57; tripartite motif containing 59; Tripartite motif-containing protein 59; TSBF1; Tumor suppressor TSBF 1; Tumor suppressor TSBF-1;
免疫原
- Q8IWR1 TRI59_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIKNVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSEITLIWFSEASLSVYQSLSNSLHKVKNILCHIFYLLKEFVWKIVSH
PTMs - Q8IWR1 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K176 | Ubiquitination | Uniprot | |
| K253 | Ubiquitination | Uniprot | |
| Y278 | Phosphorylation | Uniprot | |
| K298 | Ubiquitination | Uniprot | |
| S308 | Phosphorylation | Uniprot | |
| K310 | Acetylation | Uniprot |
研究背景
May serve as a multifunctional regulator for innate immune signaling pathways.
Endoplasmic reticulum membrane>Single-pass membrane protein.
Interacts with ECSIT.
Belongs to the TRIM/RBCC family.
Restrictive clause
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