製品: MTHFD2L Antibody
カタログ: DF16007
タンパク質の説明: Rabbit polyclonal antibody to MTHFD2L
アプリケーション: IF/ICC
反応性: Human, Mouse, Rat
分子量: 37kD(Calculated).
ユニプロット: Q9H903

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製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
MTHFD2L Antibody detects endogenous levels of MTHFD2L.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Methenyltetrahydrofolate cyclohydrolase; Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like; MTD2L_HUMAN; MTHFD2-like; MTHFD2L; NAD dependent methylenetetrahydrofolate dehydrogenase; NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2;

免疫原

免疫原:

A synthesized peptide derived from human MTHFD2L.

Uniprot:
遺伝子(ID):
発現特異性:
Q9H903 MTD2L_HUMAN:

Isoform 1, isoform 4 and isoform 5 are expressed in brain and placenta.

タンパク質配列:
MTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSAFRGFRSSGVRHEAIIISGTEMAKHIQKEIQRGVESWVSLGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRTGIQTFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVIDVGINYVHDPVTGKTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKKIIY

研究背景

細胞の位置付け:

Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Isoform 1, isoform 4 and isoform 5 are expressed in brain and placenta.

タンパク質ファミリー:

Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

研究領域

· Metabolism > Metabolism of cofactors and vitamins > One carbon pool by folate.

· Metabolism > Global and overview maps > Metabolic pathways.

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