製品: TM4SF4 Antibody
カタログ: DF15884
タンパク質の説明: Rabbit polyclonal antibody to TM4SF4
アプリケーション: IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 21kD(Calculated).
ユニプロット: P48230

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製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
TM4SF4 Antibody detects endogenous levels of TM4SF4.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

FLJ31015; il TMP; ILTMP; Intestinal and liver (il) tetraspan membrane protein; Intestine and liver tetraspan membrane protein; Lrtm4; MGC19127; Transmembrane 4 L six family member 4; transmembrane 4 L6 family member 4; Transmembrane 4 superfamily member 4;

免疫原

免疫原:

A synthesized peptide derived from human TM4SF4.

Uniprot:
遺伝子(ID):
発現特異性:
P48230 T4S4_HUMAN:

Jejunum and liver.

タンパク質配列:
MCTGGCARCLGGTLIPLAFFGFLANILLFFPGGKVIDDNDHLSQEIWFFGGILGSGVLMIFPALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKCLMANSTWGYPFHDGDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCAIQVVNGLLGTLCGDCQCCGCCGGDGPV

研究背景

機能:

Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.

PTMs:

N-glycosylated. Glycosylation is required for the growth inhibitory effect.

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Jejunum and liver.

タンパク質ファミリー:

Belongs to the L6 tetraspanin family.

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