製品: ABI3 Antibody
カタログ: DF15821
タンパク質の説明: Rabbit polyclonal antibody to ABI3
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 39kD(Calculated).
ユニプロット: Q9P2A4

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
ABI3 Antibody detects endogenous levels of ABI3.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

ABI family member 3; ABI gene family member 3; Nesh; New molecule including SH3; SSH3BP3;

免疫原

免疫原:

A synthesized peptide derived from human ABI3.

Uniprot:
遺伝子(ID):
発現特異性:
Q9P2A4 ABI3_HUMAN:

Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.

タンパク質配列:
MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSAFSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC

研究背景

機能:

May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility.

細胞の位置付け:

Cytoplasm.
Note: Colocalizes with PAK2 at leading edge of cells.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.

タンパク質ファミリー:

Belongs to the ABI family.

Restrictive clause

 

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