DUSP18 Antibody - #DF15790

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製品: DUSP18 Antibody
カタログ: DF15790
タンパク質の説明: Rabbit polyclonal antibody to DUSP18
アプリケーション: ELISA(peptide)
反応性: Human, Rat
分子量: 21kD(Calculated).
ユニプロット: Q8NEJ0

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#DF15790-BP

DUSP18 Peptide

1mg
関連ダウンロード
Antigen/Blocking Peptide MS Report
Antigen/Blocking Peptide HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
クローナリティ:
Polyclonal
特異性:
DUSP18 Antibody detects endogenous levels of DUSP18.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Dual specificity protein phosphatase 18; DUS18_HUMAN; Dusp18; LMW-DSP20; LMWDSP20; Low molecular weight dual specificity phosphatase 20;

免疫原

免疫原:

A synthesized peptide derived from human DUSP18.

Uniprot:

Q8NEJ0(DUS18_HUMAN) >>Visit HPA database.

遺伝子(ID):
DUSP18(150290)
発現特異性:
Q8NEJ0 DUS18_HUMAN:

Widely expressed with highest levels in liver, brain, ovary and testis.

タンパク質配列:
MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEKEVRLMIPL

研究背景

機能:

Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP).

細胞の位置付け:

Cytoplasm. Nucleus. Mitochondrion inner membrane>Peripheral membrane protein>Intermembrane side.
Note: Translocates to cytoplasm in response to apoptotic stimuli such as staurosporine treatment.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed with highest levels in liver, brain, ovary and testis.

タンパク質ファミリー:

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Restrictive clause

 

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For Research Use Only.
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