PROK2 Antibody - #DF15763

(1)   (2)  
製品: PROK2 Antibody
カタログ: DF15763
タンパク質の説明: Rabbit polyclonal antibody to PROK2
アプリケーション: IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 14kD(Calculated).
ユニプロット: Q9HC23

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IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
PROK2 Antibody detects endogenous levels of PROK2.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

BV8; Bv8 homolog; MIT1; PK2; PROK2; PROK2_HUMAN; Prokineticin-2; Protein Bv8 homolog;

免疫原

免疫原:

A synthesized peptide derived from human PROK2.

Uniprot:

Q9HC23(PROK2_HUMAN) >>Visit HPA database.

遺伝子(ID):
PROK2(60675)
発現特異性:
Q9HC23 PROK2_HUMAN:

Expressed in the testis and, at low levels, in the small intestine.

タンパク質配列:
MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK

研究背景

機能:

May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in the testis and, at low levels, in the small intestine.

タンパク質ファミリー:

Belongs to the AVIT (prokineticin) family.

参考文献

1). Aerosol inhalation of rhIL-10 improves acute lung injury in mice by affecting pulmonary neutrophil phenotypes through neutrophil-platelet aggregates. International immunopharmacology, 2025 (PubMed: 39778276) [IF=4.8]

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