BEX1 Antibody - #DF15606

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製品: BEX1 Antibody
カタログ: DF15606
タンパク質の説明: Rabbit polyclonal antibody to BEX1
アプリケーション: ELISA(peptide)
反応性: Human
分子量: 15kD(Calculated).
ユニプロット: Q9HBH7

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#DF15606-BP

BEX1 Peptide

1mg
関連ダウンロード
Antigen/Blocking Peptide MS Report
Antigen/Blocking Peptide HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
BEX1 Antibody detects endogenous levels of BEX1.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

BEX2; Brain expressed X linked 1; HBEX2; Protein BEX1; Reduced expression protein 3; REX 3; REX3;

免疫原

免疫原:

A synthesized peptide derived from human BEX1.

Uniprot:

Q9HBH7(BEX1_HUMAN) >>Visit HPA database.

遺伝子(ID):
BEX1(55859)
発現特異性:
Q9HBH7 BEX1_HUMAN:

Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia.

タンパク質配列:
MESKEKRAVNSLSMENANQENEEKEQVANKGEPLALPLDAGEYCVPRGNRRRFRVRQPILQYRWDMMHRLGEPQARMREENMERIGEEVRQLMEKLREKQLSHSLRAVSTDPPHHDHHDEFCLMP

研究背景

機能:

Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity).

PTMs:

Phosphorylated. Phosphorylation of Ser-102 protects it from the proteasome (By similarity).

Ubiquitinated. Degraded by the proteasome (By similarity).

細胞の位置付け:

Nucleus. Cytoplasm.
Note: Shuttles between the cytoplasm and the nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia.

タンパク質ファミリー:

Belongs to the BEX family.

Restrictive clause

 

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