製品: IFITM5 Antibody
カタログ: DF15504
タンパク質の説明: Rabbit polyclonal antibody to IFITM5
アプリケーション: IHC
反応性: Human
分子量: 14kD(Calculated).
ユニプロット: A6NNB3

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
IFITM5 Antibody detects endogenous levels of IFITM5.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Bone-restricted interferon-induced transmembrane protein-like protein; BRIL; Fragilis4; Hrmp1; IFITM5; IFM5_HUMAN; Interferon-induced transmembrane protein 5;

免疫原

免疫原:

A synthesized peptide derived from human IFITM5.

Uniprot:
遺伝子(ID):
発現特異性:
A6NNB3 IFM5_HUMAN:

Detected in bone (PubMed:24058703). Detected in osteoblasts and fibroblasts (at protein level) (PubMed:24519609). Detected in bone (PubMed:24058703). Detected in osteoblasts and fibroblasts (PubMed:24519609).

タンパク質配列:
MDTAYPREDTRAPTPSKAGAHTALTLGAPHPPPRDHLIWSVFSTLYLNLCCLGFLALAYSIKARDQKVVGDLEAARRFGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLARLAKDSAAFFSTKFDDADYD

研究背景

機能:

Required for normal bone mineralization.

PTMs:

Palmitoylated.

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Detected in bone. Detected in osteoblasts and fibroblasts (at protein level). Detected in bone. Detected in osteoblasts and fibroblasts.

タンパク質ファミリー:

Belongs to the CD225/Dispanin family.

Restrictive clause

 

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