製品: MSL3 Antibody
カタログ: DF15321
タンパク質の説明: Rabbit polyclonal antibody to MSL3
アプリケーション: ELISA(peptide)
反応性: Human, Mouse
分子量: 60kD(Calculated).
ユニプロット: Q8N5Y2

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製品説明

ソース:
Rabbit
アプリケーション:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human, Mouse
クローナリティ:
Polyclonal
特異性:
MSL3 Antibody detects endogenous levels of MSL3.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

MSL3; AU018931; DKFZp586J1822; Drosophila MSL3 like 1; Male specific lethal 3 (Drosophila) like 1; Male specific lethal 3 homolog (Drosophila); Male specific lethal 3 homolog 1 (Drosophila); Male specific lethal 3 homolog 1; Male specific lethal 3 homolog; Male specific lethal 3 like 1 (Drosophila); Male specific lethal 3 like 1; Male specific lethal 3 protein like 1; Male-specific lethal 3 homolog; Male-specific lethal-3 homolog 1; Male-specific lethal-3 protein-like 1; MS3L1_HUMAN; MSL3; MSL3 like 1; MSL3-like 1; Msl31; MSL3L1; OTTHUMP00000022911; OTTHUMP00000022912;

免疫原

免疫原:

A synthesized peptide derived from human MSL3.

Uniprot:
遺伝子(ID):
発現特異性:
Q8N5Y2 MS3L1_HUMAN:

Expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart.

タンパク質配列:
MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY

研究背景

機能:

Has a role in chromatin remodeling and transcriptional regulation. Has a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart.

Restrictive clause

 

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