製品: MYCT1 Antibody
カタログ: DF15287
タンパク質の説明: Rabbit polyclonal antibody to MYCT1
アプリケーション: WB ELISA(peptide)
反応性: Human, Mouse
分子量: 27kD(Calculated).
ユニプロット: Q8N699

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human, Mouse
クローナリティ:
Polyclonal
特異性:
MYCT1 Antibody detects endogenous levels of MYCT1.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

1110020B04Rik; AI225941; AI642973; FLJ21269; MGC156309; MGC156310; MTLC; Mtmc1; Myc target 1; Myc target in myeloid cells protein 1; Myc target protein 1; Myct1; MYCT1_HUMAN;

免疫原

免疫原:

A synthesized peptide derived from human MYCT1.

Uniprot:
遺伝子(ID):
発現特異性:
Q8N699 MYCT1_HUMAN:

Down-regulated in gastric cancer tissues.

タンパク質配列:
MRTQVYEGLCKNYFSLAVLQRDRIKLLFFDILVFLSVFLLFLLFLVDIMANNTTSLGSPWPENFWEDLIMSFTVSMAIGLVLGGFIWAVFICLSRRRRASAPISQWSSSRRSRSSYTHGLNRTGFYRHSGCERRSNLSLASLTFQRQASLEQANSFPRKSSFRASTFHPFLQCPPLPVETESQLVTLPSSNISPTISTSHSLSRPDYWSSNSLRVGLSTPPPPAYESIIKAFPDS

研究背景

機能:

May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).

細胞の位置付け:

Nucleus.
Note: Expressed in nuclei of hepatocellular carcinoma cell line BEL-7402 cells.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Down-regulated in gastric cancer tissues.

タンパク質ファミリー:

Belongs to the MYCT1 family.

Restrictive clause

 

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