製品: DSTN Antibody
カタログ: DF15268
タンパク質の説明: Rabbit polyclonal antibody to DSTN
アプリケーション: WB IHC IF/ICC
Cited expt.: WB
反応性: Human, Mouse, Rat
分子量: 19kD(Calculated).
ユニプロット: P60981

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
DSTN Antibody detects endogenous levels of DSTN.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

2610043P17Rik; ACTDP; Actin depolymerizing factor; Actin-depolymerizing factor; ADF; AU042046; bA462D18.2; corn1; DEST_HUMAN; Destrin (actin depolymerizing factor); Destrin; DSN; Dstn; Epididymis luminal protein 32; HEL32; Sid 23; sid23p;

免疫原

免疫原:

A synthesized peptide derived from human DSTN.

Uniprot:
遺伝子(ID):
発現特異性:
P60981 DEST_HUMAN:

Widely distributed in various tissues.

タンパク質配列:
MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV

研究背景

機能:

Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.

PTMs:

ISGylated.

組織特異性:

Widely distributed in various tissues.

タンパク質ファミリー:

Belongs to the actin-binding proteins ADF family.

参考文献

1). Exploring the diagnostic and immune infiltration roles of disulfidptosis related genes in pulmonary hypertension. Respiratory research, 2024 (PubMed: 39385167) [IF=4.7]

Application: WB    Species: Rat    Sample:

Fig. 8 (A) Comparison of HE staining in different groups (20X). (B) Right ventricular pressure in each group. (C) Typical bands of proteins in the Western blot experiment (mean ± SD, n = 3). (** p ≤ 0.01)

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