製品: TXNDC17 Antibody
カタログ: DF15119
タンパク質の説明: Rabbit polyclonal antibody to TXNDC17
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
分子量: 14kD(Calculated).
ユニプロット: Q9BRA2

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製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human, Mouse
クローナリティ:
Polyclonal
特異性:
TXNDC17 Antibody detects endogenous levels of TXNDC17.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

14 kDa thioredoxin-related protein; Protein 42-9-9; Thioredoxin domain-containing protein 17; Thioredoxin-like protein 5; TRP14; TXD17_HUMAN; TXNDC17;

免疫原

免疫原:

A synthesized peptide derived from human TXNDC17.

Uniprot:
遺伝子(ID):
発現特異性:
Q9BRA2 TXD17_HUMAN:

Ubiquitously expressed in cell lines.

タンパク質配列:
MARYEEVSVSGFEEFHRAVEQHNGKTIFAYFTGSKDAGGKSWCPDCVQAEPVVREGLKHISEGCVFIYCQVGEKPYWKDPNNDFRKNLKVTAVPTLLKYGTPQKLVESECLQANLVEMLFSED

研究背景

機能:

Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.

PTMs:

The oxidized protein is reduced by TRXR1.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitously expressed in cell lines.

タンパク質ファミリー:

Belongs to the thioredoxin family.

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