Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
2610208M17Rik; AIDA; AIDA_HUMAN; Axin interaction partner and dorsalization antagonist; Axin interactor; Axin interactor dorsalization associated protein; Axin interactor, dorsalization associated; C1orf80; Chromosome 1 open reading frame 80; dorsalization-associated protein; RP11-378J18.7; UPF0491 protein C1orf80;
免疫原
A synthesized peptide derived from human AIDA.
Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle.
- Q96BJ3 AIDA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE
研究背景
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle.
Belongs to the AIDA family.
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