製品: SPACA7 Antibody
カタログ: DF14964
タンパク質の説明: Rabbit polyclonal antibody to SPACA7
アプリケーション: ELISA(peptide)
反応性: Human
分子量: 21kD(Calculated).
ユニプロット: Q96KW9

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製品説明

ソース:
Rabbit
アプリケーション:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
SPACA7 Antibody detects endogenous levels of SPACA7.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Chromosome 13 open reading frame 28; FLJ27356; Protein SPACA7; SPAC7_HUMAN; Spaca7; Sperm acrosome-associated protein 7;

免疫原

免疫原:

A synthesized peptide derived from human SPACA7.

Uniprot:
遺伝子(ID):
発現特異性:
Q96KW9 SPAC7_HUMAN:

Expressed in spermatozoa (at protein level) (PubMed:22495889).

タンパク質配列:
MAVSQGDGTLCFVLLLCCWQETELRPRTVIPGSPTEIPFSSKQEDMSELLDEILVQEILDLNKTTPSEMPSTASTLSTPLHAGIDENYQAGGSENYHELLENLQFSPGIEVKISNDEANANANLHGDPSENYRGPQVSPGSEKSVSSKEKNSKNTQYENLSILDQILQNIGRSSGNIFHKEQQRTSAQRRSQGSQ

研究背景

機能:

Involved in fertilization. Seems not to play a direct role in sperm-egg binding or gamete fusion.

細胞の位置付け:

Secreted. Cytoplasmic vesicle>Secretory vesicle>Acrosome. Cytoplasmic vesicle>Secretory vesicle>Acrosome lumen.
Note: Localized in perinuclear pro-acrosomal granules in round spermatides. Localized between the inner and outer acrosomal membranes (matrix or lumen) in spermatozoa. Secreted during acrosome exocytosis.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in spermatozoa (at protein level).

Restrictive clause

 

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