SLC39A5 Antibody - #DF14954
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
LZT Hs7; MGC34778; OTTHUMP00000211153; OTTHUMP00000211154; S39A5_HUMAN; SLC39A5; solute carrier family 39 (metal ion transporter), member 5; Solute carrier family 39 member 5; Zinc transporter ZIP5 [Precursor]; Zinc transporter ZIP5; ZIP 5; ZIP-5; ZIP5; Zrt and Irt like protein 5; Zrt- and Irt-like protein 5;
免疫原
A synthesized peptide derived from human SLC39A5.
Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
- Q6ZMH5 S39A5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDLEESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG
研究背景
May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera. Seems to play a central role in controlling organismal zinc status (By similarity).
Glycosylated.
Basolateral cell membrane>Multi-pass membrane protein.
Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
Belongs to the ZIP transporter (TC 2.A.5) family.
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