製品: AKIRIN1 Antibody
カタログ: DF14690
タンパク質の説明: Rabbit polyclonal antibody to AKIRIN1
アプリケーション: ELISA(peptide)
反応性: Human
分子量: 22kD(Calculated).
ユニプロット: Q9H9L7

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製品説明

ソース:
Rabbit
アプリケーション:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
AKIRIN1 Antibody detects endogenous levels of AKIRIN1.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

AKIR1_HUMAN; AKIRIN 1; Akirin-1; Akirin1; C1orf108; FLJ12666; OTTHUMP00000008669; RP11-781D11.2; STRF2;

免疫原

免疫原:

A synthesized peptide derived from human AKIRIN1.

Uniprot:
遺伝子(ID):
発現特異性:
Q9H9L7 AKIR1_HUMAN:

Widely expressed with the highest expression in heart, liver, placenta and peripheral blood leukocytes.

タンパク質配列:
MACGATLKRPMEFEAALLSPGSPKRRRCAPLPGPTPGLRPPDAEPPPPFQTQTPPQSLQQPAPPGSERRLPTPEQIFQNIKQEYSRYQRWRHLEVVLNQSEACASESQPHSSALTAPSSPGSSWMKKDQPTFTLRQVGIICERLLKDYEDKIREEYEQILNTKLAEQYESFVKFTHDQIMRRYGTRPTSYVS

研究背景

機能:

Functions as signal transducer for MSTN during skeletal muscle regeneration and myogenesis. May regulate chemotaxis of both macrophages and myoblasts by reorganising actin cytoskeleton, leading to more efficient lamellipodia formation via a PI3 kinase dependent pathway.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed with the highest expression in heart, liver, placenta and peripheral blood leukocytes.

タンパク質ファミリー:

Belongs to the akirin family.

Restrictive clause

 

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