CCDC80 Antibody - #DF14680

(1)   (2)  
製品: CCDC80 Antibody
カタログ: DF14680
タンパク質の説明: Rabbit polyclonal antibody to CCDC80
アプリケーション: IF/ICC
Cited expt.: IF/ICC
反応性: Human, Mouse, Rat
分子量: 108kD(Calculated).
ユニプロット: Q76M96

類似製品を見る>>

   サイズ 価格 在庫状況
 100ul $280 在庫あり
 200ul $350 在庫あり

リードタイム: 当日配達

For pricing and ordering contact:
お問い合わせ先
関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
CCDC80 Antibody detects endogenous levels of CCDC80.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

2610001E17Rik; CCD50; CCD80_HUMAN; CCDC80; CL2; Coiled coil domain containing 80; Coiled coil domain containing protein 50; Coiled-coil domain-containing protein 80; Down regulated by oncogenes protein 1; Down-regulated by oncogenes protein 1; DRO1; MGC131805; MGC134851; Nuclear envelope protein okuribin; okuribin; OTTMUSP00000030743; Protein Ymer; SSG1; steroid sensitive gene 1; steroid sensitive protein 1; Up-regulated in BRS-3 deficient mouse homolog; URB;

免疫原

免疫原:

A synthesized peptide derived from human CCDC80.

Uniprot:

Q76M96(CCD80_HUMAN) >>Visit HPA database.

遺伝子(ID):
CCDC80(151887)
発現特異性:
Q76M96 CCD80_HUMAN:

Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.

タンパク質配列:
MTWRMGPRFTMLLAMWLVCGSEPHPHATIRGSHGGRKVPLVSPDSSRPARFLRHTGRSRGIERSTLEEPNLQPLQRRRSVPVLRLARPTEPPARSDINGAAVRPEQRPAARGSPREMIRDEGSSARSRMLRFPSGSSSPNILASFAGKNRVWVISAPHASEGYYRLMMSLLKDDVYCELAERHIQQIVLFHQAGEEGGKVRRITSEGQILEQPLDPSLIPKLMSFLKLEKGKFGMVLLKKTLQVEERYPYPVRLEAMYEVIDQGPIRRIEKIRQKGFVQKCKASGVEGQVVAEGNDGGGGAGRPSLGSEKKKEDPRRAQVPPTRESRVKVLRKLAATAPALPQPPSTPRATTLPPAPATTVTRSTSRAVTVAARPMTTTAFPTTQRPWTPSPSHRPPTTTEVITARRPSVSENLYPPSRKDQHRERPQTTRRPSKATSLESFTNAPPTTISEPSTRAAGPGRFRDNRMDRREHGHRDPNVVPGPPKPAKEKPPKKKAQDKILSNEYEEKYDLSRPTASQLEDELQVGNVPLKKAKESKKHEKLEKPEKEKKKKMKNENADKLLKSEKQMKKSEKKSKQEKEKSKKKKGGKTEQDGYQKPTNKHFTQSPKKSVADLLGSFEGKRRLLLITAPKAENNMYVQQRDEYLESFCKMATRKISVITIFGPVNNSTMKIDHFQLDNEKPMRVVDDEDLVDQRLISELRKEYGMTYNDFFMVLTDVDLRVKQYYEVPITMKSVFDLIDTFQSRIKDMEKQKKEGIVCKEDKKQSLENFLSRFRWRRRLLVISAPNDEDWAYSQQLSALSGQACNFGLRHITILKLLGVGEEVGGVLELFPINGSSVVEREDVPAHLVKDIRNYFQVSPEYFSMLLVGKDGNVKSWYPSPMWSMVIVYDLIDSMQLRRQEMAIQQSLGMRCPEDEYAGYGYHSYHQGYQDGYQDDYRHHESYHHGYPY

研究背景

機能:

Promotes cell adhesion and matrix assembly.

PTMs:

Phosphorylated.

細胞の位置付け:

Secreted>Extracellular space>Extracellular matrix.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.

タンパク質ファミリー:

Belongs to the CCDC80 family.

参考文献

1). Enhanced purification of uterine smooth muscle cells from adenomyosis using a novel dual-enzyme digestion method. New biotechnology, 2024 (PubMed: 39521046) [IF=4.5]

Application: IF/ICC    Species: human    Sample: P1 cells

Fig. 3. Tissue adhesion method generates progenitor cells that differentiate towards fibroblast-like cells. A. RNA velocity trajectory for all clusters shown by UMAP. B. Proportion of clusters in tissue adhesion and DM4 samples. C. Heatmap comparing highly expressed genes across all clusters. D. Feature plots demonstrating expression of fibroblast-related genes: FN1, COL1A2, COL3A1. E. Immunofluorescence images of CCDC80 and ACTA2 in P1 cells obtained from tissue adhesion and DM4. F. Immunofluorescence images of COL III and ACTA2 in P1 cells cultured continuously for 5 days. G. Statistical analysis of CCDC80/ACTA2 fluorescence expression ratio in P1 cells obtained from tissue adhesion and DM4 (n = 3, ns: non-significant, *P 

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.