製品: RAB3B Antibody
カタログ: DF14446
タンパク質の説明: Rabbit polyclonal antibody to RAB3B
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
分子量: 25kD(Calculated).
ユニプロット: P20337

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
RAB3B Antibody detects endogenous levels of total RAB3B.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Brain antigen RAB3B; RAB3B; RAB3B member RAS oncogene family; RAB3B_HUMAN; ras related protein Rab 3B; Ras-related protein Rab-3B;

免疫原

免疫原:

A synthesized peptide derived from Human RAB3B.

Uniprot:
遺伝子(ID):
タンパク質配列:
MASVTDGKTGVKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDTDPSMLGSSKNTRLSDTPPLLQQNCSC

研究背景

機能:

Protein transport. Probably involved in vesicular traffic (By similarity).

PTMs:

Phosphorylation of Thr-86 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM, CHML and RAB GDP dissociation inhibitor GDI2.

細胞の位置付け:

Cell membrane>Lipid-anchor>Cytoplasmic side. Golgi apparatus.
Note: Colocalizes with GAS8/DRC4 in the Golgi apparatus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the small GTPase superfamily. Rab family.

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