alpha 5 Defensin Antibody - #DF14360

(2)  
製品: alpha 5 Defensin Antibody
カタログ: DF14360
タンパク質の説明: Rabbit polyclonal antibody to alpha 5 Defensin
アプリケーション: IHC IF/ICC
反応性: Human
分子量: 10kD(Calculated).
ユニプロット: Q01523

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
alpha 5 Defensin Antibody detects endogenous levels of total alpha 5 Defensin.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

alpha 5; DEF5; DEF5_HUMAN; Defa; Defa29; DEFA5; Defcr29; Defcr5; Defensin 5; Defensin alpha 5; Defensin alpha 5 Paneth cell specific; Defensin alpha 5 preproprotein; Defensin; Enteric defensin; HD 5; HD5; HD5(20-94); HD5(63-94); MGC129728; RD 5;

免疫原

免疫原:

A synthesized peptide derived from Human alpha 5 Defensin.

Uniprot:

Q01523(DEF5_HUMAN) >>Visit HPA database.

遺伝子(ID):
DEFA5(1670)
発現特異性:
Q01523 DEF5_HUMAN:

Paneth cells of the small intestine (at protein level).

タンパク質配列:
MRTIAILAAILLVALQAQAESLQERADEATTQKQSGEDNQDLAISFAGNGLSALRTSGSQARATCYCRTGRCATRESLSGVCEISGRLYRLCCR

研究背景

機能:

Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.

PTMs:

Glycosylated.

細胞の位置付け:

Secreted. Cytoplasmic vesicle>Secretory vesicle.
Note: Peptides HD5(20-94), HD5(23-94) and HD5(29-94) are found within tissues, HD5(20-94) being the predominant intracellular form. Peptides HD5(56-94) and HD5(63-94) are found in the extracellular milieu, HD5(63-94) being the most abundant form.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Paneth cells of the small intestine (at protein level).

タンパク質ファミリー:

Belongs to the alpha-defensin family.

Restrictive clause

 

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