製品: Melanoma Inhibitory Activity Antibody
カタログ: DF14235
タンパク質の説明: Rabbit polyclonal antibody to Melanoma Inhibitory Activity
アプリケーション: IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 15kD(Calculated).
ユニプロット: Q16674

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
Melanoma Inhibitory Activity Antibody detects endogenous levels of total Melanoma Inhibitory Activity.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Cartilage derived retinoic acid sensitive protein; CD RAP; CDRAP; Melanoma derived growth regulatory protein precursor; Melanoma inhibitory activity protein; Melanoma-derived growth regulatory protein; Mia; MIA_HUMAN;

免疫原

免疫原:

A synthesized peptide derived from Human Melanoma Inhibitory Activity.

Uniprot:
遺伝子(ID):
発現特異性:
Q16674 MIA_HUMAN:

All malignant melanoma cell lines tested and infrequently in glioma cell lines.

タンパク質配列:
MARSLVCLGVIILLSAFSGPGVRGGPMPKLADRKLCADQECSHPISMAVALQDYMAPDCRFLTIHRGQVVYVFSKLKGRGRLFWGGSVQGDYYGDLAARLGYFPSSIVREDQTLKPGKVDVKTDKWDFYCQ

研究背景

機能:

Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.

PTMs:

May possess two intramolecular disulfide bonds.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

All malignant melanoma cell lines tested and infrequently in glioma cell lines.

タンパク質ファミリー:

Belongs to the MIA/OTOR family.

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