BDH2 Antibody - #DF14214

(2)  
製品: BDH2 Antibody
カタログ: DF14214
タンパク質の説明: Rabbit polyclonal antibody to BDH2
アプリケーション: IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 27kD; 27kD(Calculated).
ユニプロット: Q9BUT1

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MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
BDH2 Antibody detects endogenous levels of total BDH2.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

3 hydroxybutyrate dehydrogenase type 2; 3-hydroxybutyrate dehydrogenase type 2; BDH 2; BDH2; BDH2_HUMAN; Dehydrogenase/reductase (SDR family) member 6; Dehydrogenase/reductase SDR family member 6; DHRS6; EFA6R; FLJ13261; Oxidoreductase ucpA; PRO20933; R beta hydroxybutyrate dehydrogenase; R-beta-hydroxybutyrate dehydrogenase; SDR15C1; Short chain dehydrogenase/reductase family 15C member 1; UCPA OR; UNQ6308;

免疫原

免疫原:

A synthesized peptide derived from Human BDH2.

Uniprot:

Q9BUT1(BDH2_HUMAN) >>Visit HPA database.

遺伝子(ID):
BDH2(56898)
発現特異性:
Q9BUT1 BDH2_HUMAN:

Detected in liver (at protein level).

タンパク質配列:
MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL

研究背景

機能:

Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron assimilation and homeostasis. Plays a role in susceptibility to bacterial infection by providing an assimilable source of iron that is exploited by pathogenic bacteria (By similarity). Also acts as a 3-hydroxybutyrate dehydrogenase.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Detected in liver (at protein level).

サブユニット構造:

Homotetramer.

タンパク質ファミリー:

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

研究領域

· Metabolism > Lipid metabolism > Synthesis and degradation of ketone bodies.

· Metabolism > Carbohydrate metabolism > Butanoate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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