製品: RHOJ Antibody
カタログ: DF14204
タンパク質の説明: Rabbit polyclonal antibody to RHOJ
アプリケーション: IHC
反応性: Human
分子量: 24kD(Observed); 24kD(Calculated).
ユニプロット: Q9H4E5

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
RHOJ Antibody detects endogenous levels of total RHOJ.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

ARHJ; Ras homolog family member J; Ras homolog gene family member J; RAS like family 7 member B; Ras like protein family member 7B; Ras-like protein family member 7B; RASL 7B; RASL7B; Rho related GTP binding protein RhoJ; Rho-related GTP-binding protein RhoJ; RHOI; Rhoj; RHOJ_HUMAN; Tc10 like GTP binding protein TCL; TC10 like Rho GTPase; Tc10-like GTP-binding protein; TC10B; TCL;

免疫原

免疫原:

A synthesized peptide derived from Human RHOJ.

Uniprot:
遺伝子(ID):
発現特異性:
Q9H4E5 RHOJ_HUMAN:

Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver.

タンパク質配列:
MNCKEGTDSSCGCRGNDEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKRCSEGHSCCSII

研究背景

機能:

Plasma membrane-associated small GTPase specifically involved in angiogenesis. Required for endothelial cell migration during vascular development via its interaction with GLUL. Elicits the formation of F-actin-rich structures, thereby regulating endothelial cell migration.

PTMs:

Palmitoylated; regulates localization to the plasma membrane and may be mediated by GLUL.

細胞の位置付け:

Cell membrane>Lipid-anchor>Cytoplasmic side.
Note: Localization to the plasma membrane is regulated by GLUL.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver.

タンパク質ファミリー:

Belongs to the small GTPase superfamily. Rho family.

Restrictive clause

 

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