STOM Antibody - #DF13948

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製品: STOM Antibody
カタログ: DF13948
タンパク質の説明: Rabbit polyclonal antibody to STOM
アプリケーション: ELISA(peptide)
反応性: Human, Mouse, Rat
分子量: 32kD(Observed); 32kD(Calculated).
ユニプロット: P27105

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#DF13948-BP

STOM Peptide

1mg
関連ダウンロード
Antigen/Blocking Peptide MS Report
Antigen/Blocking Peptide HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
STOM Antibody detects endogenous levels of total STOM.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

BND7; EPB7; EPB72; Erythrocyte band 7 integral membrane protein; Erythrocyte membrane protein band 7.2 (stomatin); Erythrocyte surface protein band 7.2; Protein 7.2b; STOM; STOM_HUMAN; Stomatin;

免疫原

免疫原:

A synthesized peptide derived from Human STOM.

Uniprot:

P27105(STOM_HUMAN) >>Visit HPA database.

遺伝子(ID):
STOM(2040)
発現特異性:
P27105 STOM_HUMAN:

Detected in erythrocytes (at protein level). Widely expressed.

タンパク質配列:
MAEKRHTRDSEAQRLPDSFKDSPSKGLGPCGWILVAFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPIDMLQGIIGAKHSHLG

研究背景

機能:

Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.

細胞の位置付け:

Cell membrane>Peripheral membrane protein>Cytoplasmic side. Cytoplasm>Cytoskeleton. Cell membrane>Lipid-anchor>Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle.
Note: Localizes to juxtanuclear structure probably derived from the Golgi apparatus (PubMed:9243190). Colocalizes with cortical actin microfilaments at small plasma membrane protrusions (PubMed:9243190). Associates with alpha-granular lipid rafts (PubMed:12130500). Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles (PubMed:12130500). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545).

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Detected in erythrocytes (at protein level). Widely expressed.

タンパク質ファミリー:

Belongs to the band 7/mec-2 family.

Restrictive clause

 

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