製品: PRPS2 Antibody
カタログ: DF13845
タンパク質の説明: Rabbit polyclonal antibody to PRPS2
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 35kD; 35kD(Calculated).
ユニプロット: P11908

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
PRPS2 Antibody detects endogenous levels of total PRPS2.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

EC 2.7.6.1; Phosphoribosyl pyrophosphate synthase II; phosphoribosyl pyrophosphate synthetase 2; Phosphoribosyl pyrophosphate synthetase II; PPRibP; Prps2; PRPS2_HUMAN; PRS II; PRS-II; Ribose phosphate pyrophosphokinase II; Ribose-phosphate pyrophosphokinase 2;

免疫原

免疫原:

A synthesized peptide derived from Human PRPS2.

Uniprot:
遺伝子(ID):
タンパク質配列:
MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL

研究背景

機能:

Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.

サブユニット構造:

Homodimer. The active form is probably a hexamer composed of 3 homodimers (By similarity).

タンパク質ファミリー:

Belongs to the ribose-phosphate pyrophosphokinase family.

研究領域

· Metabolism > Carbohydrate metabolism > Pentose phosphate pathway.

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

· Metabolism > Global and overview maps > Carbon metabolism.

· Metabolism > Global and overview maps > Biosynthesis of amino acids.

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