AFfirm™ SIGLEC15 Mouse Monoclonal Antibody - #BF8008

(2)  
製品: SIGLEC15 Mouse Monoclonal Antibody
カタログ: BF8008
タンパク質の説明: Mouse monoclonal antibody to SIGLEC15
アプリケーション: IHC IF/ICC
反応性:
分子量: 36kD(Calculated).
ユニプロット: Q6ZMC9

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関連ダウンロード
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

クローナリティ:
Monoclonal [AFfirm8008]
特異性:
SIGLEC15 Mouse Monoclonal Antibody detects endogenous levels of total SIGLEC15.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

CD33 antigen-like 3;CD33 molecule-like 3;CD33L3;HsT1361;Sialic acid-binding Ig-like lectin 15;SIG15_HUMAN;Siglec-15;SIGLEC15;

免疫原

免疫原:

A synthesized peptide derived from human SIGLEC15.

Uniprot:

Q6ZMC9(SIG15_HUMAN) >>Visit HPA database.

遺伝子(ID):
SIGLEC15(284266)
発現特異性:
Q6ZMC9 SIG15_HUMAN:

Expressed in macrophage and/or dendritic cells of spleen and lymph nodes.

タンパク質配列:
MEKSIWLLACLAWVLPTGSFVRTKIDTTENLLNTEVHSSPAQRWSMQVPPEVSAEAGDAAVLPCTFTHPHRHYDGPLTAIWRAGEPYAGPQVFRCAAARGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADDRRYFCRVEFAGDVHDRYESRHGVRLHVTAAPRIVNISVLPSPAHAFRALCTAEGEPPPALAWSGPALGNSLAAVRSPREGHGHLVTAELPALTHDGRYTCTAANSLGRSEASVYLFRFHGASGASTVALLLGALGFKALLLLGVLAARAARRRPEHLDTPDTPPRSQAQESNYENLSQMNPRSPPATMCSP

研究背景

機能:

Binds sialylated glycoproteins.

細胞の位置付け:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in macrophage and/or dendritic cells of spleen and lymph nodes.

サブユニット構造:

Interacts with TYROBP and HCST.

タンパク質ファミリー:

Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.