Phospho-PPP1R2 (Ser120/Ser121) Antibody - #AF3977

製品: Phospho-PPP1R2 (Ser120/Ser121) Antibody
カタログ: AF3977
タンパク質の説明: Rabbit polyclonal antibody to Phospho-PPP1R2 (Ser120/Ser121)
アプリケーション: ELISA(peptide)
反応性: Human, Mouse, Rat
分子量: 23kD(Calculated).
ユニプロット: P41236
RRID: AB_2847700

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MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
Phospho-PPP1R2 (Ser120/Ser121) Antibody detects endogenous levels of PPP1R2 only when phosphorylated at Ser120/Ser121.
RRID:
AB_2847700
引用形式: Affinity Biosciences Cat# AF3977, RRID:AB_2847700.
コンジュゲート:
Unconjugated.
精製:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

IPP 2; IPP-2; IPP2; IPP2_HUMAN; MGC87148; Phosphatase inhibitor 2; Phosphoprotein phosphatase; Ppp1r2; PPP1R2 protein; Protein phosphatase 1 regulatory (inhibitor) subunit 2; Protein phosphatase 1 regulatory subunit 2; Protein phosphatase inhibitor 2;

免疫原

免疫原:

A synthesized peptide derived from human PPP1R2 around the phosphorylation site of Ser120/Ser121.

Uniprot:

P41236(IPP2_HUMAN) >>Visit HPA database.

遺伝子(ID):
PPP1R2(5504)
タンパク質配列:
MAASTASHRPIKGILKNKTSTTSSMVASAEQPRGNVDEELSKKSQKWDEMNILATYHPADKDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQEQESSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETADGESMNTEESNQGSTPSDQQQNKLRSS

研究背景

機能:

Inhibitor of protein-phosphatase 1.

PTMs:

Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.

タンパク質ファミリー:

Belongs to the protein phosphatase inhibitor 2 family.

Restrictive clause

 

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.