tenomodulin Antibody - #DF13715

(3)   (2)   Copy Info
製品: tenomodulin Antibody
カタログ: DF13715
タンパク質の説明: Rabbit polyclonal antibody to tenomodulin
アプリケーション: WB IHC
Cited expt.:
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 37kDa(Observed); 37kD(Calculated).
ユニプロット: Q9H2S6
RRID: AB_2846734

類似製品を見る>>

   サイズ 価格 在庫状況
 100ul $280 在庫あり
 200ul $350 在庫あり

リードタイム: 当日配達

For pricing and ordering contact:
お問い合わせ先
Control Products

#DF13715-BP

tenomodulin Peptide

1mg
関連ダウンロード
Antigen/Blocking Peptide MS Report
Antigen/Blocking Peptide HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
tenomodulin Antibody detects endogenous levels of total tenomodulin.
RRID:
AB_2846734
引用形式: Affinity Biosciences Cat# DF13715, RRID:AB_2846734.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

BRICD4; BRICHOS domain containing 4; CHM1 LIKE; ChM1L; Chondromodulin I like; Chondromodulin I like protein; Chondromodulin-1-like protein; Chondromodulin-I-like protein; hChM1L; hTeM; Myodulin; TeM; Tendin; Tenomodulin; Tenomodulin protein; Tnmd; TNMD_HUMAN; UNQ771/PRO1565;

免疫原

免疫原:

A synthesized peptide derived from human tenomodulin, corresponding to a region within C-terminal amino acids.

Uniprot:

Q9H2S6(TNMD_HUMAN) >>Visit HPA database.

遺伝子(ID):
TNMD(64102)
発現特異性:
Q9H2S6 TNMD_HUMAN:

Highly expressed in hypovascular connective tissues such as tendons. Has also strong expression in adipose tissue.

タンパク質配列:
MAKNPPENCEDCHILNAEAFKSKKICKSLKICGLVFGILALTLIVLFWGSKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLISVSELQDFEEEGEDLHFPANEKKGIEQNEQWVVPQVKVEKTRHARQASEEELPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Chicken
100
Rabbit
100
Zebrafish
75
Horse
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

May be an angiogenesis inhibitor.

細胞の位置付け:

Membrane>Single-pass type II membrane protein. Nucleus envelope.

Membrane>Single-pass type II membrane protein. Nucleus envelope.

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in hypovascular connective tissues such as tendons. Has also strong expression in adipose tissue.

タンパク質ファミリー:

Belongs to the chondromodulin-1 family.

参考文献

1). Natural fish swim bladder-derived MPN-nanofibrous biomimetic system exhibit ECM-responsive signal regulation and promote robust tendon-bone healing. Journal of nanobiotechnology, 2025 (PubMed: 40618081) [IF=10.2]

Application: IF/ICC    Species: Rat    Sample: BMSCs

Fig. 5 The impact of GaPP@FSB on the differentiation of BMSCs, Chondrocytes and TSPCs. Confocal laser scanning microscopy (CLSM) images showing fluorescence-labelled (A) OPN in the BMSCs (scale bar = 200 μm), and the Q-PCR data (B) revealed the expression of osteogenic differentiation-related genes in BMSCs cultured on the GaPP@FSB scaffold. Additionally, the CLSM images also showed the fluorescence-labelled (C) Tnmd in TSPCs (bar 100 μm), and Q-PCR data (D) revealed the expression of tenogenic differentiation-related genes in TSPCs cultured on the GaPP@FSB scaffold. The investigation approach for the influence of scaffolds on chondrocytes is uniform. (E) CLSM reveals the level of ACAN, a chondrocyte matrix-related proteoglycan, and (F) the Q-PCR results demonstrate the expression of genes related to chondrogenic differentiation. Data are presented as mean values ± SD, *p 
2). Hypoxia Induces HIF-1α Activation in Tendon Stem Cells to Enhance Extracellular Vesicle-Mediated Tendon Repair. ACS applied materials & interfaces, 2025 (PubMed: 40675622) [IF=8.3]
3). The treatment of acute tendon injury with small extracellular vesicles originating from TNFAIP6- ADSCs subpopoulation both in vitro and in vivo. Stem cell research & therapy, 2025 (PubMed: 41469712) [IF=7.5]

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.