| 製品: | Melanopsin Antibody |
| カタログ: | DF13615 |
| タンパク質の説明: | Rabbit polyclonal antibody to Melanopsin |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 分子量: | 52kDa(Observed); 53kD(Calculated). |
| ユニプロット: | Q9UHM6 |
| RRID: | AB_2846634 |
Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13615, RRID:AB_2846634.
免疫原
A synthesized peptide derived from human Melanopsin, corresponding to a region within C-terminal amino acids.
Eye. Expression is restricted within the ganglion and amacrine cell layers of the retina.
- Q9UHM6 OPN4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKGLIPSQDPRM
研究背景
Photoreceptor required for regulation of circadian rhythm. Contributes to pupillar reflex and other non-image forming responses to light. May be able to isomerize covalently bound all-trans retinal back to 11-cis retinal (By similarity).
Cell membrane>Multi-pass membrane protein.
Note: Found in soma, dendrites and proximal part of axons of certain retinal ganglion cells.
Eye. Expression is restricted within the ganglion and amacrine cell layers of the retina.
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
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