| 製品: | NPW Antibody |
| カタログ: | DF13576 |
| タンパク質の説明: | Rabbit polyclonal antibody to NPW |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 分子量: | 18kDa(Observed); 18kD(Calculated). |
| ユニプロット: | Q8N729 |
| RRID: | AB_2846595 |
Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13576, RRID:AB_2846595.
折りたたみ／展開
hPPL8; L8; L8C; Neuropeptide W; PPL8; PPNPW; Preproprotein L8;
免疫原
A synthesized peptide derived from human NPW, corresponding to a region within the internal amino acids.
Detected at high levels in the substantia nigra, fetal kidney and trachea; at lower levels in testis, uterus, ovary and placenta. Not detectable in many regions of the central nervous system. Also detected at high levels in lymphoblastic leukemia and colorectal adenocarcinoma.
- Q8N729 NPW_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAWRPGERGAPASRPRLALLLLLLLLPLPSGAWYKHVASPRYHTVGRAAGLLMGLRRSPYLWRRALRAAAGPLARDTLSPEPAAREAPLLLPSWVQELWETRRRSSQAGIPVRAPRSPRAPEPALEPESLDFSGAGQRLRRDVSRPAVDPAANRLGLPCLAPGPF
研究背景
Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress (By similarity). NPW23 activates GPR7 and GPR8 more efficiently than NPW30.
Secreted.
Detected at high levels in the substantia nigra, fetal kidney and trachea; at lower levels in testis, uterus, ovary and placenta. Not detectable in many regions of the central nervous system. Also detected at high levels in lymphoblastic leukemia and colorectal adenocarcinoma.
Belongs to the neuropeptide B/W family.
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