| 製品: | TIMM50 Antibody |
| カタログ: | DF13524 |
| タンパク質の説明: | Rabbit polyclonal antibody to TIMM50 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 39kDa(Observed); 40kD(Calculated). |
| ユニプロット: | Q3ZCQ8 |
| RRID: | AB_2846543 |
Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13524, RRID:AB_2846543.
折りたたみ／展開
Homolog of yeast Tim50; Import inner membrane translocase subunit TIM 50; Import inner membrane translocase subunit TIM50; Import inner membrane translocase subunit TIM50 mitochondrial; MGC102733; Mitochondrial import inner membrane translocase subunit TIM50; TIM 50; TIM 50L; TIM50; Tim50 like protein; TIM50_HUMAN; TIM50L; TIMM 50; TIMM50; translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae); Translocase of inner mitochondrial membrane 50 homolog (yeast); Translocase of inner mitochondrial membrane 50 homolog; Translocase of inner mitochondrial membrane 50, yeast, homolog of;
免疫原
A synthesized peptide derived from human TIMM50, corresponding to a region within C-terminal amino acids.
Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level).
- Q3ZCQ8 TIM50_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAASAAVFSRLRSGLRLGSRGLCTRLATPPRRAPDQAAEIGSRGSTKAQGPQQQPGSEGPSYAKKVALWLAGLLGAGGTVSVVYIFGNNPVDENGAKIPDEFDNDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLGSLTSRLWPRSKQP
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo.
May participate in the release of snRNPs and SMN from the Cajal body.
Mitochondrion inner membrane>Single-pass membrane protein.
Nucleus speckle.
Note: Nuclear and enriched in speckles with snRNPs.
Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level).
The FCP1 homology domain does not contain the canonical D-x-D-x-[TV] active site, suggesting that it probably does not display phosphatase activity in vivo.
Belongs to the TIM50 family.
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