| 製品: | Dermcidin Antibody |
| カタログ: | DF13367 |
| タンパク質の説明: | Rabbit polyclonal antibody to Dermcidin |
| アプリケーション: | WB IHC |
| 反応性: | Human, Rat |
| 分子量: | 11kDa(Observed); 11kD(Calculated). |
| ユニプロット: | P81605 |
| RRID: | AB_2846386 |
Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13367, RRID:AB_2846386.
折りたたみ／展開
AIDD; DCD 1; dcd; DCD-1; DCD_HUMAN; Dermcidin; DSEP; HCAP; PIF; Preproteolysin;
免疫原
A synthesized peptide derived from human Dermcidin, corresponding to a region within the internal amino acids.
Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml.
- P81605 DCD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRFMTLLFLTALAGALVCAYDPEAASAPGSGNPCHEASAAQKENAGEDPGLARQAPKPRKQRSSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
研究背景
DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C-terminal side of Arg and, to a lesser extent, Lys residues.
Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.
Secreted.
Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml.
Restrictive clause
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