Casein Antibody - #DF13271

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製品: Casein Antibody
カタログ: DF13271
タンパク質の説明: Rabbit polyclonal antibody to Casein
アプリケーション: WB IHC
Cited expt.: IHC
反応性: Human, Mouse, Rat
分子量: 21kDa; 22kD(Calculated).
ユニプロット: P47710
RRID: AB_2846290

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MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
Casein Antibody detects endogenous levels of total Casein.
RRID:
AB_2846290
引用形式: Affinity Biosciences Cat# DF13271, RRID:AB_2846290.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Alpha casein; alpha-S1-casein; CASA; CASA1_HUMAN; Casein alpha s1; casein, alpha; casein, alpha-S1, included; Casoxin-D; CSN1; CSN1S1; Csna; MGC149368;

免疫原

免疫原:

A synthesized peptide derived from human Casein, corresponding to a region within N-terminal amino acids.

Uniprot:

P47710(CASA1_HUMAN) >>Visit HPA database.

遺伝子(ID):
CSN1S1(1446)
発現特異性:
P47710 CASA1_HUMAN:

Mammary gland specific. Secreted in milk.

タンパク質配列:
MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQTDEIKDTRNESTQNCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQEQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNNVMLQW

研究背景

機能:

Important role in the capacity of milk to transport calcium phosphate.

Casoxin D acts as opioid antagonist and has vasorelaxing activity mediated by bradykinin B1 receptors.

PTMs:

Not glycosylated.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Mammary gland specific. Secreted in milk.

タンパク質ファミリー:

Belongs to the alpha-casein family.

参考文献

1). A Comparative Analysis of the Gene Expression Profiles in the Mammary Glands of Lactating and Nonlactating Mares at the Second Month of Gestation. Animals : an open access journal from MDPI, 2024 (PubMed: 39199853) [IF=2.7]

Application: IHC    Species: Mouse    Sample:

Figure 5. (A) Immunohistochemistry of CSN3, CSN1S1, LALBA, and LTFCSN3 proteins in mammary tissue of lactating pregnant mares. (B) Quantitative statistics for (A). (C) qPCR was used to detect expressions of CSN3, CSN1S1, LALBA, and LTF genes in equine mammary tissues. * indicates p < 0.05. Data are presented as mean ± SD (n = 3).

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