製品: ALDH1L1 Antibody
カタログ: DF13229
タンパク質の説明: Rabbit polyclonal antibody to ALDH1L1
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit
分子量: 98kDa; 99kD(Calculated).
ユニプロット: O75891
RRID: AB_2846248

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(86%), Horse(100%), Sheep(86%), Rabbit(86%)
クローナリティ:
Polyclonal
特異性:
ALDH1L1 Antibody detects endogenous levels of total ALDH1L1.
RRID:
AB_2846248
引用形式: Affinity Biosciences Cat# DF13229, RRID:AB_2846248.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

10 formyltetrahydrofolate dehydrogenase; 10 FTHFDH; 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; AL1L1_HUMAN; Aldehyde dehydrogenase 1 family member L1; Aldehyde dehydrogenase family 1 member L1; aldh1l1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; DKFZp781N0997; EC 1.5.1.6; FDH; formyltetrahydrofolate dehydrogenase; FTHFD; OTTHUMP00000155221; OTTHUMP00000214696; OTTHUMP00000214700; OTTHUMP00000222724;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
O75891 AL1L1_HUMAN:

Highly expressed in liver, pancreas and kidney.

タンパク質配列:
MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLEDGKMILASNFFKGAASSVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMASTFGDFIQLLVRKLRGDDEEGECSIDYVEMAVNKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
86
Sheep
86
Rabbit
86
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O75891 基板として

Site PTM Type Enzyme
S9 Phosphorylation
K35 Acetylation
S57 Phosphorylation
Y105 Phosphorylation
R112 Methylation
K187 Methylation
Y200 Phosphorylation
S354 Phosphorylation
S405 Phosphorylation
Y408 Phosphorylation
T613 Phosphorylation
S629 Phosphorylation
S631 Phosphorylation
K660 Acetylation
C662 S-Nitrosylation
K668 Acetylation
S825 Phosphorylation
Y848 Phosphorylation
K876 Acetylation
K882 Acetylation

研究背景

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in liver, pancreas and kidney.

タンパク質ファミリー:

In the N-terminal section; belongs to the GART family.

In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.

研究領域

· Metabolism > Metabolism of cofactors and vitamins > One carbon pool by folate.

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