製品: TGN46 Antibody
カタログ: DF13213
タンパク質の説明: Rabbit polyclonal antibody to TGN46
アプリケーション:
反応性: Human, Mouse
予測: Bovine, Rabbit, Dog
分子量: 51kDa(Observed); 46kD(Calculated).
ユニプロット: O43493
RRID: AB_2846232

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製品説明

ソース:
Rabbit
反応性:
Human, Mouse
予測:
Bovine(86%), Rabbit(%), Dog(%)
クローナリティ:
Polyclonal
特異性:
TGN46 Antibody detects endogenous levels of total TGN46.
RRID:
AB_2846232
引用形式: Affinity Biosciences Cat# DF13213, RRID:AB_2846232.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

TGN 46; TGN 51; TGN38; TGN38 homolog; TGN38B; TGN46; TGN48; TGN51; TGOLN2; TGON2_HUMAN; Trans Golgi network integral membrane protein 2; Trans golgi network protein 2; Trans Golgi network protein TGN51; Trans-Golgi network integral membrane protein 2; Trans-Golgi network protein TGN51; TTGN2;

免疫原

免疫原:

A synthesized peptide derived from human TGN46, corresponding to a region within C-terminal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
O43493 TGON2_HUMAN:

Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells.

タンパク質配列:
MRFVVALVLLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESSHFFAYLVTAAILVAVLYIAHHNKRKIIAFVLEGKRSKVTRRPKASDYQRLDQKS

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Bovine
86
Rabbit
86
Pig
0
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

May be involved in regulating membrane traffic to and from trans-Golgi network.

細胞の位置付け:

Cell membrane>Single-pass type I membrane protein. Golgi apparatus>trans-Golgi network membrane>Single-pass type I membrane protein.
Note: Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells.

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