製品: B3GNT3 Antibody
カタログ: DF12848
タンパク質の説明: Rabbit polyclonal antibody to B3GNT3
アプリケーション: WB IHC
反応性: Human, Mouse
予測: Pig, Bovine, Sheep
分子量: 43 kDa; 43kD(Calculated).
ユニプロット: Q9Y2A9
RRID: AB_2845809

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(80%), Bovine(80%), Sheep(80%)
クローナリティ:
Polyclonal
特異性:
B3GNT3 Antibody detects endogenous levels of total B3GNT3.
RRID:
AB_2845809
引用形式: Affinity Biosciences Cat# DF12848, RRID:AB_2845809.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

B3GAL T8; B3GALT8; B3GN T3; B3GNT 3; Beta 1,3 galactosyltransferase 8; Beta 3 Gal T8; Beta3Gal T8; Beta3GalT8; BGnT 3; BGnT3; Core 1 extending beta 1,3 N acetylglucosaminyltransferase; Core1 beta3GlcNAcT; HP10328; TMEM3; UDP Gal:beta GlcNAc beta 1,3 galactosyltransferase 8; UDP GlcNAc:betaGal beta 1,3 N acetylglucosaminyltransferase 3;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9Y2A9 B3GN3_HUMAN:

Expressed in colon, jejunum, stomach, esophagus, placenta and trachea.

タンパク質配列:
MKYLRHRRPNATLILAIGAFTLLLFSLLVSPPTCKVQEQPPAIPEALAWPTPPTRPAPAPCHANTSMVTHPDFATQPQHVQNFLLYRHCRHFPLLQDVPPSKCAQPVFLLLVIKSSPSNYVRRELLRRTWGRERKVRGLQLRLLFLVGTASNPHEARKVNRLLELEAQTHGDILQWDFHDSFFNLTLKQVLFLQWQETRCANASFVLNGDDDVFAHTDNMVFYLQDHDPGRHLFVGQLIQNVGPIRAFWSKYYVPEVVTQNERYPPYCGGGGFLLSRFTAAALRRAAHVLDIFPIDDVFLGMCLELEGLKPASHSGIRTSGVRAPSQRLSSFDPCFYRDLLLVHRFLPYEMLLMWDALNQPNLTCGNQTQIY

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
80
Bovine
80
Sheep
80
Dog
70
Xenopus
67
Horse
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y2A9 基板として

Site PTM Type Enzyme
Y120 Phosphorylation
S276 Phosphorylation

研究背景

機能:

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Has activity for type 2 oligosaccharides. Also acts as a core1-1,3-N-acetylglucosaminyltransferase (Core1-beta3GlcNAcT) to form the 6-sulfo sialyl Lewis x on extended core1 O-glycans.

細胞の位置付け:

Golgi apparatus membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in colon, jejunum, stomach, esophagus, placenta and trachea.

タンパク質ファミリー:

Belongs to the glycosyltransferase 31 family.

研究領域

· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - lacto and neolacto series.

· Metabolism > Global and overview maps > Metabolic pathways.

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