製品: Syntaxin3 Antibody
カタログ: DF12760
タンパク質の説明: Rabbit polyclonal antibody to Syntaxin3
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Rabbit, Dog, Chicken
分子量: 33 kDa; 33kD(Calculated).
ユニプロット: Q13277
RRID: AB_2845721

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Rabbit(86%), Dog(100%), Chicken(82%)
クローナリティ:
Polyclonal
特異性:
Syntaxin3 Antibody detects endogenous levels of total Syntaxin3.
RRID:
AB_2845721
引用形式: Affinity Biosciences Cat# DF12760, RRID:AB_2845721.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

FLJ30906; Stx3; STX3_HUMAN; STX3A; Syntaxin 3A; Syntaxin-3;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGLN

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Rabbit
86
Chicken
82
Sheep
73
Xenopus
73
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q13277 基板として

Site PTM Type Enzyme
K9 Ubiquitination
T14 Phosphorylation
K100 Ubiquitination
K117 Ubiquitination
K126 Ubiquitination
K159 Ubiquitination
K188 Ubiquitination
S192 Phosphorylation
S206 Phosphorylation
S207 Phosphorylation

研究背景

機能:

Potentially involved in docking of synaptic vesicles at presynaptic active zones.

細胞の位置付け:

Membrane>Single-pass type IV membrane protein.
Note: Localized to the inner and outer plexiform layers, the cell body and the inner segments of photoreceptors.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with REEP6 (By similarity). Interacts with PRPH2 in rod and cone photoreceptors (By similarity). Interacts with ROM1 (By similarity). Interacts with SNAP25 (By similarity). Interacts with VAMP2 (By similarity).

タンパク質ファミリー:

Belongs to the syntaxin family.

研究領域

· Genetic Information Processing > Folding, sorting and degradation > SNARE interactions in vesicular transport.

· Organismal Systems > Nervous system > Synaptic vesicle cycle.

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