製品: SLC19A3 Antibody
カタログ: DF12741
タンパク質の説明: Rabbit polyclonal antibody to SLC19A3
アプリケーション: WB
反応性: Human, Mouse, Rat
分子量: 66 kDa; 56kD(Calculated).
ユニプロット: Q9BZV2
RRID: AB_2845702

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
SLC19A3 Antibody detects endogenous levels of total SLC19A3.
RRID:
AB_2845702
引用形式: Affinity Biosciences Cat# DF12741, RRID:AB_2845702.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Solute carrier family 19 member 3; Thiamine transporter 2; thTr 2; THTR2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9BZV2 S19A3_HUMAN:

Widely expressed but most abundant in placenta, kidney and liver.

タンパク質配列:
MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAEITNEIFPVWTYSYLVLLLPVFVLTDYVRYKPVIILQGISFIITWLLLLFGQGVKTMQVVEFFYGMVTAAEVAYYAYIYSVVSPEHYQRVSGYCRSVTLAAYTAGSVLAQLLVSLANMSYFYLNVISLASVSVAFLFSLFLPMPKKSMFFHAKPSREIKKSSSVNPVLEETHEGEAPGCEEQKPTSEILSTSGKLNKGQLNSLKPSNVTVDVFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQVLNYVQILWDYKAPSQDSSIYNGAVEAIATFGGAVAAFAVGYVKVNWDLLGELALVVFSVVNAGSLFLMHYTANIWACYAGYLIFKSSYMLLITIAVFQIAVNLNVERYALVFGINTFIALVIQTIMTVIVVDQRGLNLPVSIQFLVYGSYFAVIAGIFLMRSMYITYSTKSQKDVQSPAPSENPDVSHPEEESNIIMSTKL

PTMs - Q9BZV2 基板として

Site PTM Type Enzyme
N45 N-Glycosylation
Y151 Phosphorylation
T152 Phosphorylation
S212 Phosphorylation
T234 Phosphorylation

研究背景

機能:

Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity.

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed but most abundant in placenta, kidney and liver.

タンパク質ファミリー:

Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

研究領域

· Organismal Systems > Digestive system > Vitamin digestion and absorption.

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