NOSTRIN Antibody - #DF12673
| 製品: | NOSTRIN Antibody |
| カタログ: | DF12673 |
| タンパク質の説明: | Rabbit polyclonal antibody to NOSTRIN |
| アプリケーション: | |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 58 kDa(Observed); 58kD(Calculated). |
| ユニプロット: | Q8IVI9 |
| RRID: | AB_2845635 |
Control Products
製品説明
引用形式: Affinity Biosciences Cat# DF12673, RRID:AB_2845635.
折りたたみ／展開
BM247; BM247 homolog; DaIP2; eNOS-trafficking inducer; mDaIP2; MGC20702; Nitric oxide synthase traffic inducer; Nitric oxide synthase trafficker; NOSTN_HUMAN; Nostrin; RP23-431D4.2;
免疫原
A synthesized peptide derived from human NOSTRIN, corresponding to a region within C-terminal amino acids.
Expressed at highest levels in heart, kidney, placenta and lung, and at lowest levels in brain, thymus and spleen. Present in vascular endothelial cells and placenta. Over-expressed in placenta from women with pre-eclampsia (at protein level).
- Q8IVI9 NOSTN_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRDPLTDCPYNKVYKNLKEFSQNGENFCKQVTSVLQQRANLEISYAKGLQKLASKLSKALQNTRKSCVSSAWAWASEGMKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRLQRDIEKASKDKEGLERMLKTYSSTSSFSDAKSQKDTAALMDENNLKLDLLEANSYKLSSMLAELEQRPQPSHPCSNSIFRWREKEHTHSYVKISRPFLMKRLENIVSKASSGGQSNPGSSTPAPGAAQLSSRLCKALYSFQARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGHFPAAYVEELPSNAGNTATKA
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Cell membrane>Peripheral membrane protein>Cytoplasmic side. Cytoplasmic vesicle. Cytoplasm>Cytoskeleton.
Note: Enriched in selected actin structures (PubMed:16234328, PubMed:16376344).
Nucleus.
Expressed at highest levels in heart, kidney, placenta and lung, and at lowest levels in brain, thymus and spleen. Present in vascular endothelial cells and placenta. Over-expressed in placenta from women with pre-eclampsia (at protein level).
The SH3 domain mediates interaction with NOS3, DNM2 and WASL.
The F-BAR domain is necessary for membrane targeting.
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