CCBL1/KAT1 Antibody - #DF12361
| 製品: | CCBL1/KAT1 Antibody |
| カタログ: | DF12361 |
| タンパク質の説明: | Rabbit polyclonal antibody to CCBL1/KAT1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 48-50 kDa; 48kD(Calculated). |
| ユニプロット: | Q16773 |
| RRID: | AB_2845166 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12361, RRID:AB_2845166.
折りたたみ／展開
Beta lyase; Beta lysase, kidney; CCBL 1; Cysteine conjugate beta lyase; Cysteine conjugate beta lyase, cytoplasmic; Cysteine conjugate beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase); Cysteine S conjugate beta lyase; Cytoplasmic cysteine conjugate beta lyase; FLJ95217; Glutamine phenylpyruvate aminotransferase; Glutamine transaminase K; GTK; KAT1; KATI; Kyneurenine aminotransferase; Kynurenine aminotransferase I; Kynurenine oxoglutarate transaminase 1; MGC29624; OTTHUMP00000022311; OTTHUMP00000022312;
免疫原
- Q16773 KAT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q16773 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K3 | Ubiquitination | Uniprot | |
| Y15 | Phosphorylation | Uniprot | |
| T172 | Phosphorylation | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| T182 | Phosphorylation | Uniprot | |
| K247 | Ubiquitination | Uniprot | |
| K414 | Ubiquitination | Uniprot |
研究背景
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.
Cytoplasm.
Homodimer.
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
研究領域
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Metabolism > Amino acid metabolism > Tryptophan metabolism.
· Metabolism > Metabolism of other amino acids > Selenocompound metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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