製品: ASBT Antibody
カタログ: DF12351
タンパク質の説明: Rabbit polyclonal antibody to ASBT
アプリケーション: WB IHC
反応性: Human, Mouse
分子量: 38-40 kDa(Observed); 38kD(Calculated).
ユニプロット: Q12908
RRID: AB_2845156

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Polyclonal
特異性:
ASBT Antibody detects endogenous levels of total ASBT.
RRID:
AB_2845156
引用形式: Affinity Biosciences Cat# DF12351, RRID:AB_2845156.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Apical sodium dependent bile acid transporter; Apical sodium- dependent bile acid transporter; Apical sodium-dependent bile acid transporter; ASBT; IBAT; ileal; ileal apical sodium-dependent bile acid transporter; Ileal Na(+)/bile acid cotransporter; Ileal sodium dependent bile acid transporter; Ileal sodium-dependent bile acid transporter; Ileal sodium/bile acid cotransporter; ISBT; Na(+)-dependent ileal bile acid transporter; Na+ bile acid cotransporter; Na+ dependent ileal bile acid transporter; NTCP2; NTCP2_HUMAN; PBAM; SLC10A2; Sodium/taurocholate cotransporting polypeptide; Sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family); Solute carrier family 10 (sodium/bile acid cotransporter family), member 2; Solute carrier family 10 member 2;

免疫原

免疫原:

A synthesized peptide derived from human ASBT, corresponding to a region within C-terminal amino acids.

Uniprot:
遺伝子(ID):
タンパク質配列:
MNDPNSCVDNATVCSGASCVVPESNFNNILSVVLSTVLTILLALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVSLVVPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK

研究背景

機能:

Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.

Restrictive clause

 

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.