製品: Syntaxin 16 Antibody
カタログ: DF12330
タンパク質の説明: Rabbit polyclonal antibody to Syntaxin 16
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Bovine, Dog
分子量: 42 kDa; 37kD(Calculated).
ユニプロット: O14662
RRID: AB_2845135

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Bovine(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
Syntaxin 16 Antibody detects endogenous levels of total Syntaxin 16.
RRID:
AB_2845135
引用形式: Affinity Biosciences Cat# DF12330, RRID:AB_2845135.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

hsyn16; MGC90328; Stx16; STX16_HUMAN; Syn16; Syntaxin-16;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
O14662 STX16_HUMAN:

Ubiquitous.

タンパク質配列:
MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLVGVKSR

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Dog
100
Chicken
77
Pig
75
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O14662 基板として

Site PTM Type Enzyme
T7 Phosphorylation
S17 Phosphorylation
S35 Phosphorylation
S41 Phosphorylation
S61 Phosphorylation
T71 Phosphorylation
K77 Ubiquitination
Y87 Phosphorylation
K97 Methylation
T200 Phosphorylation
T212 Phosphorylation
Y214 Phosphorylation
K281 Ubiquitination
K287 Ubiquitination
K301 Ubiquitination

研究背景

機能:

SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.

細胞の位置付け:

Golgi apparatus membrane>Single-pass type IV membrane protein.

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

サブユニット構造:

Interacts with GCC2. Interacts with BAIAP3; this interaction is increased in the presence of calcium.

タンパク質ファミリー:

Belongs to the syntaxin family.

研究領域

· Genetic Information Processing > Folding, sorting and degradation > SNARE interactions in vesicular transport.

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